A theophylline based copper N-heterocyclic carbene complex: synthesis and activity studies in green media†
Abstract
The synthesis of an easily accessible theophylline-derived copper complex with additional ammonium functionalization has been developed. This xanthine-based metal compound turned out to be an active initiator of the alkyne–azide cycloaddition reaction (CuAAC) and Glaser homo-coupling reaction in aqueous media at room temperature.