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Issue 38, 2016
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Two step label free particle separation in a microfluidic system using elasto-inertial focusing and magnetophoresis

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Abstract

This study focuses on the separation of different sized particles and cells by employing a facile two step label free separation technique which consists of elasto-inertial particle focusing and magnetophoretic particle repulsion. The elasto-inertial force makes the objects migrate toward the centerline at the first stage, and the magnetophoretic repulsion force makes them migrate to the lateral direction depending upon their particle size at the second stage in the microchannel. An analytical calculation is carried out to predict the trajectories of different sized particles by considering hydrodynamic viscous drag and magnetophoretic repulsion forces, and this is compared to the experimental results. Numerical analyses are performed to understand the physics underlying the elasto-inertial particle focusing and the magnetophoretic particle migration.

Graphical abstract: Two step label free particle separation in a microfluidic system using elasto-inertial focusing and magnetophoresis

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Publication details

The article was received on 03 Feb 2016, accepted on 15 Mar 2016 and first published on 17 Mar 2016


Article type: Paper
DOI: 10.1039/C6RA03146C
Citation: RSC Adv., 2016,6, 32090-32097
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    Two step label free particle separation in a microfluidic system using elasto-inertial focusing and magnetophoresis

    M. J. Kim, D. J. Lee, J. R. Youn and Y. S. Song, RSC Adv., 2016, 6, 32090
    DOI: 10.1039/C6RA03146C

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