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Issue 12, 2016
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Self-healing hydrogels triggered by amino acids

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Nine amino acids with different chemical properties have been chosen to promote the formation of hydrogels based on the bolamphiphilic gelator A: three basic amino acids (arginine, histidine and lysine), one acidic amino acid (aspartic acid), two neutral aliphatic amino acids (alanine and serine) and three neutral aromatic amino acids (phenylalanine, tyrosine and tryptophan). Although hydrogels are obtained under any conditions, strong and thermoreversible hydrogels are formed by the addition of Arg to the bolamphiphilic gelator. These hydrogels have physiological pH and self-healing properties and may be used for regenerative medicine applications.

Graphical abstract: Self-healing hydrogels triggered by amino acids

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Publication details

The article was received on 20 Aug 2016, accepted on 27 Sep 2016 and first published on 28 Sep 2016

Article type: Research Article
DOI: 10.1039/C6QO00476H
Citation: Org. Chem. Front., 2016,3, 1699-1704
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    Self-healing hydrogels triggered by amino acids

    N. Zanna, A. Merlettini and C. Tomasini, Org. Chem. Front., 2016, 3, 1699
    DOI: 10.1039/C6QO00476H

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