Jump to main content
Jump to site search

Issue 11, 2016
Previous Article Next Article

Facile synthesis of annulated heterocyclic benzo[kl]acridine derivatives via one-pot N–H/C–H coupling

Author affiliations

Abstract

An efficient N–H/C–H one-pot coupling method for the preparation of benzo[kl]acridines has been developed based on palladium-catalyzed domino synthesis. Using commercially available starting materials such as dihalonaphthalenes and diphenylamines, and combining amination with catalysts for C–H activation, up to 95% overall yield can be achieved.

Graphical abstract: Facile synthesis of annulated heterocyclic benzo[kl]acridine derivatives via one-pot N–H/C–H coupling

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 19 Jul 2016, accepted on 13 Sep 2016, published on 14 Sep 2016 and first published online on 14 Sep 2016


Article type: Tutorial Account
DOI: 10.1039/C6QO00371K
Citation: Org. Chem. Front., 2016,3, 1520-1523
  •   Request permissions

    Facile synthesis of annulated heterocyclic benzo[kl]acridine derivatives via one-pot N–H/C–H coupling

    Y. Zagranyarski, A. Skabeev, Y. Ma, K. Müllen and C. Li, Org. Chem. Front., 2016, 3, 1520
    DOI: 10.1039/C6QO00371K

Search articles by author