Issue 6, 2016

Conformations of large macrocycles and ring-in-ring complexes

Abstract

A kinetically directed, stepwise approach towards molecular Borromean links enabled the isolation and structural characterization of synthetic intermediates along the way. Here we report the synthesis and crystal structures of three flexible macrocyclic intermediates and a new ring-in-ring complex, anchored together through ruthenium(II) centers, which contains open terpyridine caps in the inner Ring II. Terpyridines circumvent the conformational cis/trans limitations of bipyridines and the new ring-in-ring complex forms tetrametallic complexes with Zn(II), Pt(II) and Ru(III) metal ions. Analysis of the four macrocyclic structures provides a good foundation for the conformational flexibility in these complexes and demonstrates the robust applicability of the terpyridine design elements towards the engineered synthesis of ring-in-ring topologies.

Graphical abstract: Conformations of large macrocycles and ring-in-ring complexes

Supplementary files

Article information

Article type
Research Article
Submitted
16 Jan 2016
Accepted
08 Mar 2016
First published
23 Mar 2016
This article is Open Access
Creative Commons BY license

Org. Chem. Front., 2016,3, 661-666

Conformations of large macrocycles and ring-in-ring complexes

J. K. Klosterman, J. Veliks, D. K. Frantz, Y. Yasui, M. Loepfe, E. Zysman-Colman, A. Linden and J. S. Siegel, Org. Chem. Front., 2016, 3, 661 DOI: 10.1039/C6QO00024J

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements