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Issue 45, 2016
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Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

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Abstract

To provide a molecular insight for guiding polymer coating in surface science and nanotechnology, here we examined the structures of brushed polyethylene glycol(bPEG)- and phosphorylcholine(bPC)-grafted iron oxide nanoparticles and analyzed their protein avoiding properties. We show bPC as an advantageous biomimetic alternative to PEG in rendering stealth nanostructures.

Graphical abstract: Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

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Publication details

The article was received on 25 Aug 2016, accepted on 22 Sep 2016 and first published on 23 Sep 2016


Article type: Communication
DOI: 10.1039/C6PY01480A
Citation: Polym. Chem., 2016,7, 6875-6879
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    Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

    B. Wang, T. Blin, A. Käkinen, X. Ge, E. H. Pilkington, J. F. Quinn, M. R. Whittaker, T. P. Davis, P. C. Ke and F. Ding, Polym. Chem., 2016, 7, 6875
    DOI: 10.1039/C6PY01480A

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