Issue 25, 2016

Mitochondria-targeted fluorescent polymersomes for drug delivery to cancer cells

Abstract

Mitochondria are an attractive target to deliver anticancer drugs. We have synthesized a cationic triphenylphosphonium ion conjugated fluorescent polymer which self-assembles into nanosized polymersomes and targets the encapsulated anticancer drug doxorubicin to cancer cell mitochondria.

Graphical abstract: Mitochondria-targeted fluorescent polymersomes for drug delivery to cancer cells

Supplementary files

Article information

Article type
Communication
Submitted
08 Apr 2016
Accepted
22 May 2016
First published
24 May 2016

Polym. Chem., 2016,7, 4151-4154

Author version available

Mitochondria-targeted fluorescent polymersomes for drug delivery to cancer cells

P. S. Kulkarni, M. K. Haldar, M. I. Confeld, C. J. Langaas, X. Yang, S. Y. Qian and S. Mallik, Polym. Chem., 2016, 7, 4151 DOI: 10.1039/C6PY00623J

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