Jump to main content
Jump to site search

Issue 42, 2016
Previous Article Next Article

Intramolecular oxyacetoxylation of N-allylamides: an expeditious synthesis of oxazolines and oxazines by using a PhI(OAc)2/hydrogen fluoride–pyridine system

Author affiliations

Abstract

The synthesis of oxazolines and oxazines from N-allylamides was accomplished via an unprecedented reaction set. This reaction involved an intramolecular cyclization of N-allylamides resulting from nucleophilic attack of the allylamine on the benzoxazin-4-one. Unlike the previous literature, the isolable N-allylamide could readily be subjected to exo and endo fashion ring-closure under conditions to afford the title compounds.

Graphical abstract: Intramolecular oxyacetoxylation of N-allylamides: an expeditious synthesis of oxazolines and oxazines by using a PhI(OAc)2/hydrogen fluoride–pyridine system

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Aug 2016, accepted on 01 Oct 2016 and first published on 04 Oct 2016


Article type: Paper
DOI: 10.1039/C6OB01752E
Citation: Org. Biomol. Chem., 2016,14, 10074-10079
  •   Request permissions

    Intramolecular oxyacetoxylation of N-allylamides: an expeditious synthesis of oxazolines and oxazines by using a PhI(OAc)2/hydrogen fluoride–pyridine system

    J. Ranjith, N. Rajesh, B. Sridhar and P. Radha Krishna, Org. Biomol. Chem., 2016, 14, 10074
    DOI: 10.1039/C6OB01752E

Search articles by author

Spotlight

Advertisements