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Issue 43, 2016
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Biologically active γ-lactams: synthesis and natural sources

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Abstract

The γ-lactam moiety is present in a large number of natural and non-natural biologically active compounds. The range of biological activities covered by these compounds is very broad. Functionalized γ-lactams are thus of high interest and have great potential in medicinal chemistry. This review provides a description of the title compounds by focusing on their synthesis, natural sources and biological activities.

Graphical abstract: Biologically active γ-lactams: synthesis and natural sources

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Publication details

The article was received on 22 Jun 2016, accepted on 05 Oct 2016 and first published on 07 Oct 2016


Article type: Review Article
DOI: 10.1039/C6OB01349J
Citation: Org. Biomol. Chem., 2016,14, 10134-10156
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    Biologically active γ-lactams: synthesis and natural sources

    J. Caruano, G. G. Muccioli and R. Robiette, Org. Biomol. Chem., 2016, 14, 10134
    DOI: 10.1039/C6OB01349J

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