Issue 6, 2016
From the journal:

Organic & Biomolecular Chemistry

Synthesis and evaluation of a desymmetrised synthetic lectin: an approach to carbohydrate receptors with improved versatility†

Tiddo J. Mooibroek,*a   Matthew P. Crumpa  and  Anthony P. Davis*a  

* Corresponding authors

a School of Chemistry, University of Bristol, Cantock's Close, Bristol, UK
E-mail: tiddomooibroek@gmail.com, anthony.davis@bristol.ac.uk

Abstract

A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M−1 are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.

Graphical abstract: Synthesis and evaluation of a desymmetrised synthetic lectin: an approach to carbohydrate receptors with improved versatility

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6OB00023A
Article type
Communication
Submitted
06 Jan 2016
Accepted
14 Jan 2016
First published
14 Jan 2016
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2016,14, 1930-1933

Permissions

Request permissions

Synthesis and evaluation of a desymmetrised synthetic lectin: an approach to carbohydrate receptors with improved versatility

T. J. Mooibroek, M. P. Crump and A. P. Davis, Org. Biomol. Chem., 2016, 14, 1930 DOI: 10.1039/C6OB00023A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements