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Issue 5, 2016
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Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

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Abstract

Simultaneous tracking of nanoparticles and encapsulated payload is of great importance and visualizing their activity is arduous. Here we use vibrational spectroscopy to study the in vitro tracking of co-localized lipid nanoparticles and encapsulated drug employing a model system derived from doxorubicin-encapsulated deuterated phospholipid (dodecyl phosphocholine-d38) single tailed phospholipid vesicles.

Graphical abstract: Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

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The article was received on 12 Nov 2015, accepted on 03 Jan 2016 and first published on 05 Jan 2016


Article type: Paper
DOI: 10.1039/C5NR07975F
Author version available: Download Author version (PDF)
Citation: Nanoscale, 2016,8, 2826-2831
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    Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

    S. K. Misra, P. Mukherjee, A. Ohoka, A. S. Schwartz-Duval, S. Tiwari, R. Bhargava and D. Pan, Nanoscale, 2016, 8, 2826
    DOI: 10.1039/C5NR07975F

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