Jump to main content
Jump to site search

Issue 11, 2016
Previous Article Next Article

Cobalt catalysed, copper assisted C(sp2)–P cross coupling

Author affiliations

Abstract

An efficient protocol for the cross coupling of styrenyl/aryl halides and H-phosphinate has been developed using a unique Co/Cu catalytic system in the absence of any additional ligand for the first time. A library of diversely functionalised styrenyl/aryl phosphonates has been synthesized using this procedure. The advantages offered using this procedure are operational simplicity, the use of inexpensive and relatively benign metals as a catalyst, wide tolerance to functionality including electron withdrawing and releasing substituents, excellent stereoselectivity and high yields. The mechanism has also been established. The unique feature of this Co/Cu system is that, it primarily involves Co in the catalytic cycle and Cu in the transmetalation process.

Graphical abstract: Cobalt catalysed, copper assisted C(sp2)–P cross coupling

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Jul 2016, accepted on 21 Sep 2016 and first published on 22 Sep 2016


Article type: Paper
DOI: 10.1039/C6NJ02247B
Citation: New J. Chem., 2016,40, 9556-9564
  •   Request permissions

    Cobalt catalysed, copper assisted C(sp2)–P cross coupling

    T. Ghosh, P. Maity, D. Kundu and B. C. Ranu, New J. Chem., 2016, 40, 9556
    DOI: 10.1039/C6NJ02247B

Search articles by author

Spotlight

Advertisements