Issue 9, 2016

Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC

Abstract

Cyclic olefin copolymer (COC) is widely used in microfluidics due to its UV-transparency, its biocompatibility and high chemical resistance. Here we present a fast and cost-effective solvent bonding technique, which allows for the efficient bonding of protein-patterned COC structures. The bonding process is carried out at room temperature and takes less than three minutes. Enzyme activity is retained upon bonding and microstructure deformation does not occur.

Graphical abstract: Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC

Article information

Article type
Communication
Submitted
07 Dec 2015
Accepted
21 Mar 2016
First published
23 Mar 2016
This article is Open Access
Creative Commons BY license

Lab Chip, 2016,16, 1561-1564

Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC

N. Keller, T. M. Nargang, M. Runck, F. Kotz, A. Striegel, K. Sachsenheimer, D. Klemm, K. Länge, M. Worgull, C. Richter, D. Helmer and B. E. Rapp, Lab Chip, 2016, 16, 1561 DOI: 10.1039/C5LC01498K

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