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Issue 21, 2016
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Lewis acid-catalyzed 2-arylquinazoline formation from N′-arylbenzimidamides and paraformaldehyde

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Abstract

An efficient procedure for the synthesis of 2-arylquinazolines from N′-arylbenzimidamides has been developed under transition-metal-free conditions. In this process, stable and low-toxicity paraformaldehyde was used as the carbon source. A broad range of functional groups were well tolerated in this reaction system.

Graphical abstract: Lewis acid-catalyzed 2-arylquinazoline formation from N′-arylbenzimidamides and paraformaldehyde

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Publication details

The article was received on 19 Aug 2016, accepted on 19 Sep 2016 and first published on 19 Sep 2016


Article type: Communication
DOI: 10.1039/C6GC02319C
Citation: Green Chem., 2016,18, 5773-5776
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    Lewis acid-catalyzed 2-arylquinazoline formation from N′-arylbenzimidamides and paraformaldehyde

    X. Cheng, H. Wang, F. Xiao and G. Deng, Green Chem., 2016, 18, 5773
    DOI: 10.1039/C6GC02319C

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