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Volume 196, 2017
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AIE fluorophore with enhanced cellular uptake for tracking esterase-activated release of taurine and ROS scavenging

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Abstract

Fluorophores with aggregation-induced emission (AIE) characteristics are attractive and versatile tools for both chemical sensing and biological imaging. Herein, we designed and synthesized a fluorescent light-up system CTPE-Tau with enhanced cellular uptake ability. The system possesses several advantages, such as a large Stokes shift, low cytotoxicity, and good photostability. Also, it has been successfully utilized to track esterase-activated release of taurine and to scavenge intracellular ROS, and shows great potential for trackable visualized therapy.

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Publication details

The article was received on 06 May 2016, accepted on 14 Jun 2016 and first published on 14 Jun 2016


Article type: Paper
DOI: 10.1039/C6FD00118A
Citation: Faraday Discuss., 2017,196, 335-350
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    AIE fluorophore with enhanced cellular uptake for tracking esterase-activated release of taurine and ROS scavenging

    J. Wang, Y. Wu, F. Zeng, S. Huang and S. Wu, Faraday Discuss., 2017, 196, 335
    DOI: 10.1039/C6FD00118A

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