Jump to main content
Jump to site search

Issue 4, 2016
Previous Article Next Article

Toxicity of dimercaptosuccinate-coated and un-functionalized magnetic iron oxide nanoparticles towards aquatic organisms

Author affiliations

Abstract

Magnetic iron oxide nanoparticles (IONP) have gained growing attention in recent years for their promising applications in medical treatment and environmental remediation. Among the IONP, dimercaptosuccinic acid coated-IONP (DMSA-IONP) have great potential because of their rapid uptake into cells and their potential to effectively adsorb heavy metals. The widespread use and potential release of IONP into the environment raises concern about their environmental impact. To date, little is known about the consequences of the exposure of aquatic organisms to such particles. In this context we investigated the colloidal stability of DMSA-IONP in different test media as well as their effects on green algae (Raphidocelis subcapitata), duckweed (Lemna minor) and water fleas (Daphnia magna). Moreover, a comparative analysis of stability and ecotoxicity data of DMSA-IONP with freshly prepared and aged uncoated IONP dispersions was performed, considering the importance of stability of particles in determining their toxicity. The green algae were the most sensitive organism with EC50 values (72 h) ranging between 0.86–2.27 μM Fe (i.e. 0.05 to 0.13 mg Fe L−1) for the three types of IONP. The observed flocculation and (co-)sedimentation of algae with IONP are assumed to reduce the access of cells to nutrients and light. Lemna was not affected by any of the IONP due to the low availability of IONP induced by fast aggregation of IONP in the medium. Minor toxic effects on Daphnia were found for uncoated IONP (EC50 between 374–1181 μM Fe, i.e. 21–66 mg Fe L−1) after 72 h. However, the ingestion and accumulation of coated and uncoated IONP in the gastrointestinal tract of daphnids was observed. Our evaluation of IONP has revealed a certain hazard potential to aquatic organisms. In this light it appears important to prevent the release of large amounts of IONP into the environment, which might limit their applicability.

Graphical abstract: Toxicity of dimercaptosuccinate-coated and un-functionalized magnetic iron oxide nanoparticles towards aquatic organisms

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 16 Oct 2015, accepted on 13 May 2016, published on 16 May 2016 and first published online on 16 May 2016


Article type: Paper
DOI: 10.1039/C5EN00222B
Citation: Environ. Sci.: Nano, 2016,3, 754-767
  • Open access: Creative Commons BY license
  •   Request permissions

    Toxicity of dimercaptosuccinate-coated and un-functionalized magnetic iron oxide nanoparticles towards aquatic organisms

    Y. Zhang, R. Dringen, C. Petters, W. Rastedt, J. Köser, J. Filser and S. Stolte, Environ. Sci.: Nano, 2016, 3, 754
    DOI: 10.1039/C5EN00222B

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author