Issue 13, 2016

Removing the superfluous: a supported squaramide catalyst with a minimalistic linker applied to the enantioselective flow synthesis of pyranonaphthoquinones

Abstract

A continuous flow setup has been implemented for the enantioselective production of a library of pyranonaphthoquinones. This was possible through a sequential two-step process involving a squaramide-catalyzed Michael reaction and oxa-Michael cyclization. A key factor for the success of this methodology was the development of a new, cost-effective polystyrene-supported squaramide.

Graphical abstract: Removing the superfluous: a supported squaramide catalyst with a minimalistic linker applied to the enantioselective flow synthesis of pyranonaphthoquinones

Supplementary files

Article information

Article type
Communication
Submitted
03 Mar 2016
Accepted
18 Mar 2016
First published
21 Mar 2016

Catal. Sci. Technol., 2016,6, 4686-4689

Author version available

Removing the superfluous: a supported squaramide catalyst with a minimalistic linker applied to the enantioselective flow synthesis of pyranonaphthoquinones

L. Osorio-Planes, C. Rodríguez-Escrich and M. A. Pericàs, Catal. Sci. Technol., 2016, 6, 4686 DOI: 10.1039/C6CY00473C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements