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Physical Chemistry Chemical Physics

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Paper

Dynamics of the conformational transitions during the dimerization of an intrinsically disordered peptide: a case study on the human islet amyloid polypeptide fragment

Qin Qiao,*a   Ruxi Qi,b   Guanghong Wei*b and   Xuhui Huang*cde  
*
Corresponding authors
a
Hefei National Laboratory for Physical Sciences at the Microscale and Collaborative Innovation Center of Chemistry for Energy Materials (iChEM), University of Science and Technology of China, Hefei, China
E-mail: qinqiao@connect.ust.hk
b
State Key Laboratory of Surface Physics, Key Laboratory for Computational Physical Sciences (MOE), and Department of Physics, Fudan University, Shanghai, China
E-mail: ghwei@fudan.edu.cn
c
Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
E-mail: xuhuihuang@ust.hk
d
Division of Biomedical Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
e
Center of Systems Biology and Human Health, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
Phys. Chem. Chem. Phys., 2016,18, 29892-29904

DOI: 10.1039/C6CP05590G
Received 12 Aug 2016, Accepted 28 Sep 2016
First published online 28 Sep 2016
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