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Issue 48, 2016
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Solvent penetration mediated phase transformation for the preparation of aggregated particles with well-defined shape

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Abstract

We report here a unique method for the preparation of aggregated crystals with well-defined shape and size using a solvent penetration-mediated phase transformation. An unusually fast phase transformation of sulfadiazine was observed. The aggregated sulfadiazine crystals are obtained through a water penetration mediated transformation of sulfadiazine N-methyl pyrrolidone solvate. The aggregated particles keep the same shape and size of the parent crystals.

Graphical abstract: Solvent penetration mediated phase transformation for the preparation of aggregated particles with well-defined shape

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Publication details

The article was received on 19 Aug 2016, accepted on 27 Sep 2016 and first published on 27 Sep 2016


Article type: Communication
DOI: 10.1039/C6CE01808D
Citation: CrystEngComm, 2016,18, 9223-9226
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    Solvent penetration mediated phase transformation for the preparation of aggregated particles with well-defined shape

    S. Wu, M. Chen, K. Li, S. Xu, B. Yu, S. Liu, B. Hou and J. Gong, CrystEngComm, 2016, 18, 9223
    DOI: 10.1039/C6CE01808D

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