Jump to main content
Jump to site search

Issue 87, 2016
Previous Article Next Article

Condensation of anthranilic acids with pyridines to furnish pyridoquinazolones via pyridine dearomatization

Author affiliations

Abstract

The unprecedented carbodiimide-mediated condensation between pyridines and anthranilic acids via pyridine dearomatization at room temperature has been developed to provide a straightforward approach to pyridoquinazolones. The value of this approach has further been demonstrated by its application to one-step, gram-scale syntheses of a series of pyridoquinazolone-based natural products and their analogues from readily available starting materials.

Graphical abstract: Condensation of anthranilic acids with pyridines to furnish pyridoquinazolones via pyridine dearomatization

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 Sep 2016, accepted on 04 Oct 2016 and first published on 05 Oct 2016


Article type: Communication
DOI: 10.1039/C6CC07365D
Citation: Chem. Commun., 2016,52, 12869-12872
  •   Request permissions

    Condensation of anthranilic acids with pyridines to furnish pyridoquinazolones via pyridine dearomatization

    Y. Yang, C. Zhu, M. Zhang, S. Huang, J. Lin, X. Pan and W. Su, Chem. Commun., 2016, 52, 12869
    DOI: 10.1039/C6CC07365D

Search articles by author

Spotlight

Advertisements