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Issue 1, 2017
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Fluorescent glycoprobes: a sweet addition for improved sensing

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Abstract

The development of small-molecule fluorescent probes for the detection of ions and biomacromolecules and for cellular and in vivo imaging has been a very active research area. Nevertheless, many problems exist for traditional probes including their poor water solubility, toxicity and the inability to target specific tissues. Because of the enhanced water solubility, biocompatibility and targeting ability for specific cells, there has been an emerging movement to use carbohydrates as either the backbone or as a warhead to decorate conventional fluorescent probes, producing “glycoprobes” with enhanced properties. This feature article provides an overview of recently developed glycoprobes for ion and protein detection as well as targeted (receptor targeting) cellular imaging and theranostics. Here, we summarise the tactics for preparing small molecular glycoprobes and their supramolecular 2D material composites.

Graphical abstract: Fluorescent glycoprobes: a sweet addition for improved sensing

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Publication details

The article was received on 22 Aug 2016, accepted on 03 Oct 2016 and first published on 04 Oct 2016


Article type: Feature Article
DOI: 10.1039/C6CC06875H
Citation: Chem. Commun., 2017,53, 82-90
  • Open access: Creative Commons BY license
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    Fluorescent glycoprobes: a sweet addition for improved sensing

    X. He, Y. Zang, T. D. James, J. Li, G. Chen and J. Xie, Chem. Commun., 2017, 53, 82
    DOI: 10.1039/C6CC06875H

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