Issue 85, 2016
From the journal:

Chemical Communications

Embedding magnetic nanoparticles into coordination polymers to mimic zinc ion transporters for targeted tumor therapy†

Enguo Ju,ab   Zhaowei Chen,a   Wei Li,ab   Kai Dong,a   ZhenZhen Wang,ab   Zhen Liu,a   Fang Pu,a   Jinsong Ren*a  and  Xiaogang Qu*a  

* Corresponding authors

a Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
E-mail: jren@ciac.ac.cn, xqu@ciac.ac.cn

b University of Chinese Academy of Sciences, Beijing, China

Abstract

Magnetic nanoparticle-embedded coordination polymers could act as mimics for zinc ion transporters for targeted cancer therapy. Compared with traditional zinc ionophores, our system could realize targeted and internal environment responsive transport of zinc ions to suppress the tumour growth while minimizing nonspecific injury to normal tissues.

Graphical abstract: Embedding magnetic nanoparticles into coordination polymers to mimic zinc ion transporters for targeted tumor therapy

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Article information

DOI
https://doi.org/10.1039/C6CC06467A
Article type
Communication
Submitted
05 Aug 2016
Accepted
23 Sep 2016
First published
27 Sep 2016

Chem. Commun., 2016,52, 12598-12601

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Embedding magnetic nanoparticles into coordination polymers to mimic zinc ion transporters for targeted tumor therapy

E. Ju, Z. Chen, W. Li, K. Dong, Z. Wang, Z. Liu, F. Pu, J. Ren and X. Qu, Chem. Commun., 2016, 52, 12598 DOI: 10.1039/C6CC06467A

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