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Issue 86, 2016
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A ligation-based loop-mediated isothermal amplification (ligation-LAMP) strategy for highly selective microRNA detection

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Abstract

A novel ligation-based loop-mediated isothermal amplification (ligation-LAMP) method has been developed for miRNA detection, which enables highly selective and sensitive quantitative detection of miR-21 in a dynamic range from 1 fM to 1 nM with the ability to discriminate single-base mismatches.

Graphical abstract: A ligation-based loop-mediated isothermal amplification (ligation-LAMP) strategy for highly selective microRNA detection

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Publication details

The article was received on 26 Jul 2016, accepted on 27 Sep 2016 and first published on 30 Sep 2016


Article type: Communication
DOI: 10.1039/C6CC06160E
Citation: Chem. Commun., 2016,52, 12721-12724
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    A ligation-based loop-mediated isothermal amplification (ligation-LAMP) strategy for highly selective microRNA detection

    W. Du, M. Lv, J. Li, R. Yu and J. Jiang, Chem. Commun., 2016, 52, 12721
    DOI: 10.1039/C6CC06160E

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