Issue 59, 2016

DNA-catalyzed glycosylation using aryl glycoside donors

Abstract

We report the identification by in vitro selection of Zn2+/Mn2+-dependent deoxyribozymes that glycosylate the 3′-OH of a DNA oligonucleotide. Both β and α anomers of aryl glycosides can be used as the glycosyl donors. Individual deoxyribozymes are each specific for a particular donor anomer.

Graphical abstract: DNA-catalyzed glycosylation using aryl glycoside donors

Associated articles

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Article information

Article type
Communication
Submitted
23 May 2016
Accepted
18 Jun 2016
First published
22 Jun 2016
This article is Open Access
Creative Commons BY license

Chem. Commun., 2016,52, 9259-9262

DNA-catalyzed glycosylation using aryl glycoside donors

A. R. Hesser, B. M. Brandsen, S. M. Walsh, P. Wang and S. K. Silverman, Chem. Commun., 2016, 52, 9259 DOI: 10.1039/C6CC04329A

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