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Issue 59, 2016
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DNA-catalyzed glycosylation using aryl glycoside donors

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Abstract

We report the identification by in vitro selection of Zn2+/Mn2+-dependent deoxyribozymes that glycosylate the 3′-OH of a DNA oligonucleotide. Both β and α anomers of aryl glycosides can be used as the glycosyl donors. Individual deoxyribozymes are each specific for a particular donor anomer.

Graphical abstract: DNA-catalyzed glycosylation using aryl glycoside donors

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Publication details

The article was received on 23 May 2016, accepted on 18 Jun 2016 and first published on 22 Jun 2016


Article type: Communication
DOI: 10.1039/C6CC04329A
Citation: Chem. Commun., 2016,52, 9259-9262
  • Open access: Creative Commons BY license
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    DNA-catalyzed glycosylation using aryl glycoside donors

    A. R. Hesser, B. M. Brandsen, S. M. Walsh, P. Wang and S. K. Silverman, Chem. Commun., 2016, 52, 9259
    DOI: 10.1039/C6CC04329A

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