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Issue 59, 2016
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Paramagnetic lanthanide chelates for multicontrast MRI

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Abstract

The preparation of a paramagnetic chelator that serves as a platform for multicontrast MRI, and can be utilized either as a T1-weighted, paraCEST or 19F MRI contrast agent is reported. Its europium(III) complex exhibits an extremely slow water exchange rate which is optimal for the use in CEST MRI. The potential of this platform was demonstrated through a series of MRI studies on tube phantoms and animals.

Graphical abstract: Paramagnetic lanthanide chelates for multicontrast MRI

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Publication details

The article was received on 12 May 2016, accepted on 02 Jun 2016 and first published on 02 Jun 2016


Article type: Communication
DOI: 10.1039/C6CC04011J
Citation: Chem. Commun., 2016,52, 9224-9227
  • Open access: Creative Commons BY license
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    Paramagnetic lanthanide chelates for multicontrast MRI

    N. Cakić, T. Savić, J. Stricker-Shaver, V. Truffault, C. Platas-Iglesias, C. Mirkes, R. Pohmann, K. Scheffler and G. Angelovski, Chem. Commun., 2016, 52, 9224
    DOI: 10.1039/C6CC04011J

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