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Issue 39, 2016
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Stabilisation of an amorphous form of ROY through a predicted co-former interaction

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Abstract

The highly polymorphic compound ROY, notorious for the colour of its crystals, was the subject of an optimised high-throughput ultrasound-based co-crystal screen. This screen involved a computational pre-screen which highlighted an interaction between ROY and the potential co-former pyrogallol. We have shown that the presence of pyrogallol stabilises the amorphous form of ROY, highlighting the potential for future prediction of co-amorphous behaviours.

Graphical abstract: Stabilisation of an amorphous form of ROY through a predicted co-former interaction

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Publication details

The article was received on 08 Apr 2016, accepted on 18 Apr 2016 and first published on 18 Apr 2016


Article type: Communication
DOI: 10.1039/C6CC02949C
Citation: Chem. Commun., 2016,52, 6537-6540
  • Open access: Creative Commons BY license
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    Stabilisation of an amorphous form of ROY through a predicted co-former interaction

    P. A. Corner, J. J. Harburn, J. W. Steed, J. F. McCabe and D. J. Berry, Chem. Commun., 2016, 52, 6537
    DOI: 10.1039/C6CC02949C

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