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Issue 34, 2016
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Acetazolamide polymorphism: a case of hybridization induced polymorphism?

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Abstract

The unusual phenomenon of the formation of the kinetic form as against the thermodynamic form upon slow cooling of boiling aqueous solution in the case of diuretic drug acetazolamide is rationalized in terms of “hybridization induced polymorphism” based on extensive experimental and theoretical investigations.

Graphical abstract: Acetazolamide polymorphism: a case of hybridization induced polymorphism?

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Publication details

The article was received on 22 Feb 2016, accepted on 17 Mar 2016 and first published on 21 Mar 2016


Article type: Communication
DOI: 10.1039/C6CC01612J
Citation: Chem. Commun., 2016,52, 5820-5823
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    Acetazolamide polymorphism: a case of hybridization induced polymorphism?

    S. Sarkar, M. S. Pavan, S. Cherukuvada and T. N. Guru Row, Chem. Commun., 2016, 52, 5820
    DOI: 10.1039/C6CC01612J

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