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Issue 31, 2016
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Copper-catalyzed oxidative coupling between quinazoline 3-oxides and unactivated aldehydes: an efficient approach to functionalized quinazolines

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Abstract

A copper-catalyzed oxidative coupling between quinazoline 3-oxides and unactivated aldehydes was described. The reaction worked well for both aliphatic and aromatic aldehydes and produced not only the direct oxidative coupling ketones but also cyclic hydroxamic esters derived from quinazolines.

Graphical abstract: Copper-catalyzed oxidative coupling between quinazoline 3-oxides and unactivated aldehydes: an efficient approach to functionalized quinazolines

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Publication details

The article was received on 02 Feb 2016, accepted on 29 Feb 2016 and first published on 07 Mar 2016


Article type: Communication
DOI: 10.1039/C6CC00946H
Citation: Chem. Commun., 2016,52, 5375-5378
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    Copper-catalyzed oxidative coupling between quinazoline 3-oxides and unactivated aldehydes: an efficient approach to functionalized quinazolines

    L. Fan, T. Wang, Y. Tian, F. Xiong, S. Wu, Q. Liang and J. Zhao, Chem. Commun., 2016, 52, 5375
    DOI: 10.1039/C6CC00946H

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