The synthesis and efficient one-pot catalytic “self-breeding” of asymmetrical NC(sp3)E-hybridised pincer complexes

Abstract

Cyclopalladation of the pyridyl-substituted chiral phosphine sulfide (N–PS) and oxide (N–PO) compounds afforded the asymmetric N–C(sp³)*–S and N–C(sp³)*–O pincer complexes. When applied as catalysts in asymmetric hydrophosphination, the newly developed aliphatic pincer catalyst could be recycled over three runs and obtained in large quantities via a one-pot “self-breeding” catalytic protocol.