Issue 15, 2016

Trifluoromethyl nitrogen heterocycles: synthetic aspects and potential biological targets

Abstract

Recent advances regarding the synthetic chemistry of fluorinated aziridines, azetidines, pyrrolidines and their lactam/amino acid counterparts are presented. These heterocycles are of high importance both as building blocks for more complex structures and as active parts of medicinal chemistry-oriented compounds.

Graphical abstract: Trifluoromethyl nitrogen heterocycles: synthetic aspects and potential biological targets

Article information

Article type
Feature Article
Submitted
13 Nov 2015
Accepted
14 Jan 2016
First published
14 Jan 2016

Chem. Commun., 2016,52, 3077-3094

Author version available

Trifluoromethyl nitrogen heterocycles: synthetic aspects and potential biological targets

F. Meyer, Chem. Commun., 2016, 52, 3077 DOI: 10.1039/C5CC09414C

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