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Issue 15, 2016
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A new ratiometric fluorescent probe for rapid, sensitive and selective detection of endogenous hydrogen sulfide in mitochondria

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Abstract

We have developed a new ratiometric fluorescent probe composed of a coumarin–merocyanine dyad based on the FRET mechanism. The probe showed clear dual-emission signal changes in blue and red spectral windows upon addition of H2S in a dose dependent manner under a single wavelength excitation. The probe targeted mitochondria with high selectivity and sensitivity toward H2S.

Graphical abstract: A new ratiometric fluorescent probe for rapid, sensitive and selective detection of endogenous hydrogen sulfide in mitochondria

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Publication details

The article was received on 09 Nov 2015, accepted on 19 Jan 2016 and first published on 19 Jan 2016


Article type: Communication
DOI: 10.1039/C5CC09267A
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2016,52, 3131-3134
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    A new ratiometric fluorescent probe for rapid, sensitive and selective detection of endogenous hydrogen sulfide in mitochondria

    X. Feng, T. Zhang, J. Liu, J. Miao and B. Zhao, Chem. Commun., 2016, 52, 3131
    DOI: 10.1039/C5CC09267A

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