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Issue 8, 2016
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Control of DNA origami inter-tile connection with vertical linkers

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Abstract

This communication describes a new method that enables high yield assembly along both of the two-dimensional edges of DNA origami tiles by controlling the Mg2+ concentration; high Mg2+ concentrations promote linkage connections between the vertical edges of the tiles. As a demonstration, DNA origami dimers assembled from two rectangular origami along the vertical edges are used as scaffolds for the double sided assembly of gold nanoparticles with different inter-particle spacings.

Graphical abstract: Control of DNA origami inter-tile connection with vertical linkers

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Publication details

The article was received on 03 Oct 2015, accepted on 21 Nov 2015 and first published on 24 Nov 2015


Article type: Communication
DOI: 10.1039/C5CC08185H
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2016,52, 1610-1613
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    Control of DNA origami inter-tile connection with vertical linkers

    R. Wang, K. Gorday, C. Nuckolls and S. J. Wind, Chem. Commun., 2016, 52, 1610
    DOI: 10.1039/C5CC08185H

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