Issue 3, 2016

Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation

Abstract

Recent studies have demonstrated that metal–organic frameworks can be employed as protective coatings for enzymes. Two efficient strategies have been reported for the synthesis of such composite materials: biomimetic mineralisation and controlled co-precipitation using polyvinylpyrrolidone. We assessed the relative efficacy of each approach by comparing the thermal stability of encapsulated urease. The resulting data shows that over a range of temperatures biomimetic mineralisation offers superior protection than the co-precipitation method.

Graphical abstract: Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation

Supplementary files

Article information

Article type
Communication
Submitted
10 Sep 2015
Accepted
30 Oct 2015
First published
02 Nov 2015

Chem. Commun., 2016,52, 473-476

Author version available

Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation

K. Liang, C. J. Coghlan, S. G. Bell, C. Doonan and P. Falcaro, Chem. Commun., 2016, 52, 473 DOI: 10.1039/C5CC07577G

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