Jump to main content
Jump to site search

Issue 5, 2016
Previous Article Next Article

Quantitative carbon detector for enhanced detection of molecules in foods, pharmaceuticals, cosmetics, flavors, and fuels

Author affiliations

Abstract

Analysis of trace compounds, such as pesticides and other contaminants, within consumer products, fuels, and the environment requires quantification of increasingly complex mixtures of difficult-to-quantify compounds. Many compounds of interest are non-volatile and exhibit poor response in current gas chromatography and flame ionization systems. Here we show the reaction of trimethylsilylated chemical analytes to methane using a quantitative carbon detector (QCD; the Polyarc™ reactor) within a gas chromatograph (GC), thereby enabling enhanced detection (up to 10×) of highly functionalized compounds including carbohydrates, acids, drugs, flavorants, and pesticides. Analysis of a complex mixture of compounds shows that the GC-QCD method exhibits faster and more accurate analysis of complex mixtures commonly encountered in everyday products and the environment.

Graphical abstract: Quantitative carbon detector for enhanced detection of molecules in foods, pharmaceuticals, cosmetics, flavors, and fuels

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Dec 2015, accepted on 30 Jan 2016 and first published on 01 Feb 2016


Article type: Communication
DOI: 10.1039/C5AN02552D
Citation: Analyst, 2016,141, 1627-1632
  •   Request permissions

    Quantitative carbon detector for enhanced detection of molecules in foods, pharmaceuticals, cosmetics, flavors, and fuels

    C. A. Beach, C. Krumm, C. S. Spanjers, S. Maduskar, A. J. Jones and P. J. Dauenhauer, Analyst, 2016, 141, 1627
    DOI: 10.1039/C5AN02552D

Search articles by author

Spotlight

Advertisements