Jump to main content
Jump to site search

Issue 24, 2015
Previous Article Next Article

Time-dependent gel to gel transformation of a peptide based supramolecular gelator

Author affiliations

Abstract

A dipeptide with a long fatty acid chain at its N-terminus gives hydrogels in phosphate buffer in the pH range 7.0–8.5. The hydrogel with a gelator concentration of 0.45% (w/v) at pH 7.46 (physiological pH) provides a very good platform to study dynamic changes within a supramolecular framework as it exhibits remarkable change in its appearance with time. Interestingly, the first formed transparent hydrogel gradually transforms into a turbid gel within 2 days. These two forms of the hydrogel have been thoroughly investigated by using small angle X-ray scattering (SAXS), powder X-ray diffraction (PXRD), field emission scanning electron microscopic (FE-SEM) and high-resolution transmission electron microscopic (HR-TEM) imaging, FT-IR and rheometric analyses. The SAXS and low angle PXRD studies substantiate different packing arrangements for the gelator molecules for these two different gel states (the freshly prepared and the aged hydrogel). Moreover, rheological studies of these two gels reveal that the aged gel is stiffer than the freshly prepared gel.

Graphical abstract: Time-dependent gel to gel transformation of a peptide based supramolecular gelator

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Apr 2015, accepted on 20 May 2015 and first published on 20 May 2015


Article type: Paper
DOI: 10.1039/C5SM00808E
Citation: Soft Matter, 2015,11, 4944-4951
  •   Request permissions

    Time-dependent gel to gel transformation of a peptide based supramolecular gelator

    A. Baral, S. Basak, K. Basu, A. Dehsorkhi, I. W. Hamley and A. Banerjee, Soft Matter, 2015, 11, 4944
    DOI: 10.1039/C5SM00808E

Search articles by author

Spotlight

Advertisements