Jump to main content
Jump to site search

Issue 2, 2015
Previous Article Next Article

Direct catalytic cross-coupling of alkenyllithium compounds

Author affiliations

Abstract

A catalytic method for the direct cross-coupling of alkenyllithium reagents with aryl and alkenyl halides is described. The use of a catalyst comprising Pd2(dba)3/XPhos allows for the stereoselective preparation of a wide variety of substituted alkenes in high yields under mild conditions. In addition (1-ethoxyvinyl)lithium can be efficiently converted into substituted vinyl ethers which, after hydrolysis, give readily access to the corresponding methyl ketones in a one pot procedure.

Graphical abstract: Direct catalytic cross-coupling of alkenyllithium compounds

Back to tab navigation

Supplementary files

Publication details

The article was received on 10 Oct 2014, accepted on 26 Nov 2014 and first published on 28 Nov 2014


Article type: Edge Article
DOI: 10.1039/C4SC03117B
Citation: Chem. Sci., 2015,6, 1394-1398
  • Open access: Creative Commons BY license
  •   Request permissions

    Direct catalytic cross-coupling of alkenyllithium compounds

    V. Hornillos, M. Giannerini, C. Vila, M. Fañanás-Mastral and B. L. Feringa, Chem. Sci., 2015, 6, 1394
    DOI: 10.1039/C4SC03117B

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements