Issue 113, 2015
From the journal:

RSC Advances

Mild deuteration method of terminal alkynes in heavy water using reusable basic resin†

Tsuyoshi Yamada,a   Kwihwan Park,a   Yasunari Monguchi,a   Yoshinari Sawama*a  and  Hironao Sajiki*a  

* Corresponding authors

a Laboratory of Organic Chemistry, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan
E-mail: sawama@gifu-pu.ac.jp, sajiki@gifu-pu.ac.jp
Fax: +81-58-230-8109
Tel: +81-58-230-8109

Abstract

The mild and efficient deuteration of terminal alkynes (mono-substituted alkynes) proceeded in the presence of a basic anion exchange resin, WA30, which is a polystyrene polymer bearing a tertiary amine residue on the aromatic nuclei, in heavy water (D2O) at room temperature. WA30 could be easily removed by a simple filtration and repeatedly reused.

Graphical abstract: Mild deuteration method of terminal alkynes in heavy water using reusable basic resin

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5RA18921G
Article type
Communication
Submitted
15 Sep 2015
Accepted
22 Oct 2015
First published
23 Oct 2015

RSC Adv., 2015,5, 92954-92957

Author version available

Download author version (PDF)

Permissions

Request permissions

Mild deuteration method of terminal alkynes in heavy water using reusable basic resin

T. Yamada, K. Park, Y. Monguchi, Y. Sawama and H. Sajiki, RSC Adv., 2015, 5, 92954 DOI: 10.1039/C5RA18921G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements