Palladium(ii)-catalyzed Sequential ortho-olefination of β-arylethamines with assistance of oxalyl amide†
Abstract
Pd-catalyzed highly selective ortho-alkenylation of β-arylethamines with the assistance of oxalyl amide is developed. A wide range of olefins such as allyl acetate, allyl alcohol derivatives, terminal alkenes, acraldehyde, acrylate, acrylonitrile, neohexene and styrene derivatives are all tolerable, which is the broadest yet reported for this kind of C–H transformation. Furthermore, sequential functionalization of β-arylethamine is also achieved well in one pot.