One-pot synthesis of trisubstituted ureas from α-chloroaldoxime O-methanesulfonates and secondary amines†
Abstract
Trisubstituted ureas can be synthesized in a one-pot fashion from bench-stable α-chloroaldoxime O-methanesulfonates and secondary amines under mild reaction conditions. Two practical protocols have been developed to achieve various urea syntheses from both secondary aromatic amines and aliphatic amines.
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