A combination of trimethylsilyl chloride and hydrous natural montmorillonite clay: an efficient solid acid catalyst for the azidation of benzylic and allylic alcohols with trimethylsilyl azide

Abstract

We present a new procedure to convert in situ natural montmorillonite clay into a partially acidified one using a catalytic amount of trimethylsilyl chloride and trace water. We demonstrate that the acidic montmorillonite can catalyze the direct azidation of various benzylic and allylic alcohols with trimethylsilyl azide.