Nonlinear optical properties of Au/Ag alloyed nanoboxes and their applications in both in vitro and in vivo bioimaging under long-wavelength femtosecond laser excitation

Kanghui Li; Yalun Wang; Fuhong Cai; Jiaxin Yu; Shaowei Wang; Zhenfeng Zhu; Liliang Chu; Hequn Zhang; Jun Qian; Sailing He

doi:10.1039/C4RA10752G

Nonlinear optical properties of Au/Ag alloyed nanoboxes and their applications in both in vitro and in vivo bioimaging under long-wavelength femtosecond laser excitation†

Kanghui Li,^a Yalun Wang,^a Fuhong Cai,^a Jiaxin Yu,^a Shaowei Wang,^a Zhenfeng Zhu,^a Liliang Chu,^a Hequn Zhang,^a Jun Qian*^a and Sailing He*^a

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* Corresponding authors

^a State Key Laboratory of Modern Optical Instrumentation (Zhejiang University), Centre for Optical and Electromagnetic Research, Zhejiang Provincial Key Laboratory for Sensing Technologies, JORCEP (Sino-Swedish Joint Research Center of Photonics), Zhejiang University, Hangzhou, 310058 China
E-mail: qianjun@zju.edu.cn, sailing@kth.se

Abstract

We synthesize Au/Ag alloyed nanoboxes (ANBs) with different LSPR (localized surface plasmon resonance) peak wavelengths and observe their various nonlinear optical properties. Both in vitro and in vivo bioimaging results show that Au/Ag ANBs are very good candidates for high-contrast and deep-tissue nonlinear optical imaging with negligible photothermal toxicity.

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Nonlinear optical properties of Au/Ag alloyed nanoboxes and their applications in both in vitro and in vivo bioimaging under long-wavelength femtosecond laser excitation†

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Nonlinear optical properties of Au/Ag alloyed nanoboxes and their applications in both in vitro and in vivo bioimaging under long-wavelength femtosecond laser excitation

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