Issue 44, 2015
From the journal:

Organic & Biomolecular Chemistry

Directing-group-assisted copper-catalyzed oxidative esterification of phenols with aldehydes†

Yong Zheng,‡a   Wei-Bin Song‡a  and  Li-Jiang Xuan*a  

* Corresponding authors

a State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China
E-mail: ljxuan@mail.shcnc.ac.cn
Fax: +86-21-20231968
Tel: +86-21-20231968

Abstract

A directing-group-assisted copper-catalyzed oxidative esterification of phenols with aldehydes using TBHP as an oxidant was described. This methodology which showed the advantages of base, ligand free, short routes and functional group tolerance could be used as an alternative protocol for the classical esterification reactions.

Graphical abstract: Directing-group-assisted copper-catalyzed oxidative esterification of phenols with aldehydes

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Article information

DOI
https://doi.org/10.1039/C5OB01465D
Article type
Paper
Submitted
20 Jul 2015
Accepted
25 Aug 2015
First published
25 Aug 2015

Org. Biomol. Chem., 2015,13, 10834-10843

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Directing-group-assisted copper-catalyzed oxidative esterification of phenols with aldehydes

Y. Zheng, W. Song and L. Xuan, Org. Biomol. Chem., 2015, 13, 10834 DOI: 10.1039/C5OB01465D

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