Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 26, 2015
Previous Article Next Article

Current complexity: a tool for assessing the complexity of organic molecules

Author affiliations

Abstract

Molecular complexity for a synthetic organic chemist is difficult to define, though intuitively known. Despite the importance of this concept, the quantitative assessment of complexity within organic chemistry has remained a challenge. We report here on the development of an approach for generating a unique complexity index, which is reflective of both intrinsic molecular complexity and extrinsic synthetic complexity. This index is based on a community's perception of complexity, within the context of current technology, calculating a molecule's current complexity. Our approach allows for a direct comparison between molecules, the analysis of trends within research programs, it enables an assessment (and comparison) of new synthetic approaches to known molecules and is capable of following a molecule's apparent complexity as it changes over time.

Graphical abstract: Current complexity: a tool for assessing the complexity of organic molecules

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 08 Apr 2015, accepted on 30 Apr 2015 and first published on 12 May 2015


Article type: Paper
DOI: 10.1039/C5OB00709G
Citation: Org. Biomol. Chem., 2015,13, 7164-7176
  •   Request permissions

    Current complexity: a tool for assessing the complexity of organic molecules

    J. Li and M. D. Eastgate, Org. Biomol. Chem., 2015, 13, 7164
    DOI: 10.1039/C5OB00709G

Search articles by author