Jump to main content
Jump to site search

Issue 6, 2015
Previous Article Next Article

A BODIPY-luminol chemiluminescent resonance energy-transfer (CRET) cassette for imaging of cellular superoxide

Author affiliations

Abstract

Spectroscopic and in cellulo studies are here reported on the very first BODIPY-luminol chemiluminescent resonance energy-transfer (CRET) cassette where the luminol CL agent is covalently linked to the BODIPY energy-transfer acceptor in a molecular dyad. The efficiency of intramolecular CRET investigated for the BODIPY-luminol dyad was found to be 64% resulting in a dual emissive response. Successful in cellulo biochemiluminescence via CRET was achieved in PMA activated splenocytes.

Graphical abstract: A BODIPY-luminol chemiluminescent resonance energy-transfer (CRET) cassette for imaging of cellular superoxide

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 Nov 2014, accepted on 02 Dec 2014 and first published on 02 Dec 2014


Article type: Paper
DOI: 10.1039/C4OB02413C
Author version available: Download Author version (PDF)
Citation: Org. Biomol. Chem., 2015,13, 1763-1767
  •   Request permissions

    A BODIPY-luminol chemiluminescent resonance energy-transfer (CRET) cassette for imaging of cellular superoxide

    S. Bag, J.-C. Tseng and J. Rochford, Org. Biomol. Chem., 2015, 13, 1763
    DOI: 10.1039/C4OB02413C

Search articles by author

Spotlight

Advertisements