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Issue 8, 2015
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Functional chromatographic technique for natural product isolation

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Abstract

Natural product discovery arises through a unique interplay between chromatographic purification and biological assays. Currently, most techniques used for natural product purification deliver leads without a defined biological action. We now describe a technique, referred to herein as functional chromatography, that deploys biological affinity as the matrix for compound isolation.

Graphical abstract: Functional chromatographic technique for natural product isolation

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Publication details

The article was received on 28 Oct 2014, accepted on 02 Jan 2015 and first published on 14 Jan 2015


Article type: Communication
DOI: 10.1039/C4OB02292K
Author version available: Download Author version (PDF)
Citation: Org. Biomol. Chem., 2015,13, 2255-2259
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    Functional chromatographic technique for natural product isolation

    E. C. Lau, D. J. Mason, N. Eichhorst, P. Engelder, C. Mesa, E. M. Kithsiri Wijeratne, G. M. K. B. Gunaherath, A. A. L. Gunatilaka, J. J. La Clair and E. Chapman, Org. Biomol. Chem., 2015, 13, 2255
    DOI: 10.1039/C4OB02292K

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