Issue 8, 2015

Functional chromatographic technique for natural product isolation

Abstract

Natural product discovery arises through a unique interplay between chromatographic purification and biological assays. Currently, most techniques used for natural product purification deliver leads without a defined biological action. We now describe a technique, referred to herein as functional chromatography, that deploys biological affinity as the matrix for compound isolation.

Graphical abstract: Functional chromatographic technique for natural product isolation

Supplementary files

Article information

Article type
Communication
Submitted
28 Oct 2014
Accepted
02 Jan 2015
First published
14 Jan 2015

Org. Biomol. Chem., 2015,13, 2255-2259

Author version available

Functional chromatographic technique for natural product isolation

E. C. Lau, D. J. Mason, N. Eichhorst, P. Engelder, C. Mesa, E. M. Kithsiri Wijeratne, G. M. K. B. Gunaherath, A. A. L. Gunatilaka, J. J. La Clair and E. Chapman, Org. Biomol. Chem., 2015, 13, 2255 DOI: 10.1039/C4OB02292K

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