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Issue 1, 2015
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Corrin-based chemosensors for the ASSURED detection of endogenous cyanide

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Abstract

Cassava (Manihot esculenta Crantz) is a staple food for more than 500 million people, especially in Africa and South America. However, its consumption bears risks as it contains cyanogenic glycosides that convert enzymatically to toxic cyanide during cell damage. To avoid serious health problems by unintentional cyanide intake, this dangerous product of decomposition must be removed before consumption. For monitoring such food processing procedures and for controlling the quality and safety of cassava products on the market, a convenient and reliable analytical method for routine applications without laboratory equipment is required. This Perspective summarizes the authors’ work on corrin-based chemosensors for the (‘naked-eye’) detection of endogenous cyanide in cassava samples. Considering selectivity, sensitivity, handling and speed of detection, these systems are superior to currently applied methods. Based on these properties, the development of a test kit for application by rural farmers in remote locations is proposed.

Graphical abstract: Corrin-based chemosensors for the ASSURED detection of endogenous cyanide

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Publication details

The article was received on 04 Sep 2014, accepted on 09 Oct 2014 and first published on 15 Oct 2014


Article type: Perspective
DOI: 10.1039/C4OB01889C
Citation: Org. Biomol. Chem., 2015,13, 14-17
  • Open access: Creative Commons BY license
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    Corrin-based chemosensors for the ASSURED detection of endogenous cyanide

    F. Zelder and L. Tivana, Org. Biomol. Chem., 2015, 13, 14
    DOI: 10.1039/C4OB01889C

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