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Issue 22, 2015
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Design of ultrasensitive DNA-based fluorescent pH sensitive nanodevices

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Abstract

Here we tune the pH sensitivity of a DNA-based conformational switch, called the I-switch, to yield a set of fluorescent pH sensitive nanodevices with a collective, expanded pH sensing regime from 5.3 to 7.5. The expanded pH regime of this new family of I-switches originates from a dramatic improvement in the overall percentage signal change in response to pH of these nanodevices.

Graphical abstract: Design of ultrasensitive DNA-based fluorescent pH sensitive nanodevices

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Publication details

The article was received on 18 Feb 2015, accepted on 06 May 2015 and first published on 20 May 2015


Article type: Communication
DOI: 10.1039/C5NR01158B
Author version available: Download Author version (PDF)
Citation: Nanoscale, 2015,7, 10008-10012
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    Design of ultrasensitive DNA-based fluorescent pH sensitive nanodevices

    S. Halder and Y. Krishnan, Nanoscale, 2015, 7, 10008
    DOI: 10.1039/C5NR01158B

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