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Issue 10, 2015
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Nanocarriers in therapy of infectious and inflammatory diseases

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Abstract

Nanotechnology is a growing science that has applications in various areas of medicine. The composition of nanocarriers for drug delivery is critical to guarantee high therapeutic performance when targeting specific host sites. Applications of nanotechnology are prevalent in the diagnosis and treatment of infectious and inflammatory diseases. This review summarizes recent advancements in the application of nanotechnology to the therapy of infectious and inflammatory diseases. The major focus is on the design and fabrication of various nanomaterials, characteristics and physicochemical properties of drug-loaded nanocarriers, and the use of these nanoscale drug delivery systems in treating infectious and inflammatory diseases, such as AIDS, hepatitis, tuberculosis, melanoma, and representative inflammatory diseases. Clinical trials and future perspective of the use of nanocarriers are also discussed in detail. We hope that such a review will be valuable to researchers who are exploring nanoscale drug delivery systems for the treatment of specific infectious and inflammatory diseases.

Graphical abstract: Nanocarriers in therapy of infectious and inflammatory diseases

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Publication details

The article was received on 31 Dec 2014, accepted on 05 Feb 2015 and first published on 06 Feb 2015


Article type: Review Article
DOI: 10.1039/C4NR07682F
Citation: Nanoscale, 2015,7, 4291-4305
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    Nanocarriers in therapy of infectious and inflammatory diseases

    U. Ikoba, H. Peng, H. Li, C. Miller, C. Yu and Q. Wang, Nanoscale, 2015, 7, 4291
    DOI: 10.1039/C4NR07682F

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