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Issue 16, 2015
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Nanoscale materials for hyperthermal theranostics

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Abstract

Recently, the use of nanoscale materials has attracted considerable attention with the aim of designing personalized therapeutic approaches that can enhance both spatial and temporal control over drug release, permeability, and uptake. Potential benefits to patients include the reduction of overall drug dosages, enabling the parallel delivery of different pharmaceuticals, and the possibility of enabling additional functionalities such as hyperthermia or deep-tissue imaging (LIF, PET, etc.) that complement and extend the efficacy of traditional chemotherapy and surgery. This mini-review is focused on an emerging class of nanometer-scale materials that can be used both to heat malignant tissue to reduce angiogenesis and DNA-repair while simultaneously offering complementary imaging capabilities based on radioemission, optical fluorescence, magnetic resonance, and photoacoustic methods.

Graphical abstract: Nanoscale materials for hyperthermal theranostics

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Publication details

The article was received on 19 Oct 2014, accepted on 10 Mar 2015 and first published on 18 Mar 2015


Article type: Feature Article
DOI: 10.1039/C4NR06164K
Citation: Nanoscale, 2015,7, 7115-7126
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    Nanoscale materials for hyperthermal theranostics

    B. E. Smith, P. B. Roder, X. Zhou and P. J. Pauzauskie, Nanoscale, 2015, 7, 7115
    DOI: 10.1039/C4NR06164K

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