Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity†
Abstract
We report the synthesis and biological evaluation of a series of
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* Corresponding authors
a
Key Laboratory of Radiopharmaceuticals (Beijing Normal University), Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China
E-mail:
hmjia@bnu.edu.cn
Fax: +86 10 58808891
Tel: +86 10 58808891
b Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, POB 510119, D-01314 Dresden, Germany
c Technische Universität Dresden, Department of Chemistry and Food Chemistry, D-01062 Dresden, Germany
d Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 231 S. 34th Street, Philadelphia, PA 19104, USA
We report the synthesis and biological evaluation of a series of
F. Xie, T. Kniess, C. Neuber, W. Deuther-Conrad, C. Mamat, B. P. Lieberman, B. Liu, R. H. Mach, P. Brust, J. Steinbach, J. Pietzsch and H. Jia, Med. Chem. Commun., 2015, 6, 1093 DOI: 10.1039/C5MD00079C
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